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(2025) demonstrated that USP2 deletion in mice impairs synchrony among SCN neurons, dampens molecular rhythms, and alters behavioral circadian outputs, reinforcing USP2s role in maintaining coherence within the central clock network (Srikanta et al., 2025)

Alpha diversity analysis (Shannon and Simpson index) demonstrated that TLYY significantly restored the DSS-induced reduction in microbial diversity (Figures 5A,B)

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The onset of withdrawal symptoms after a rapid reduction in opioid dosage, or because of the administration of an antagonist, defines physical dependence

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